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15 Collectively, these events lead to a vicious cycle of persistent inflammation and chronic oxidative stress, which results in protease-anti-protease imbalance, defects in tissue repair mechanisms, accelerated apoptosis in lung cells and progression of COPD

In patients with poorly controlled hypertension (n = 16, age 57 9), 400 mg/d oral BH 4 for 4 weeks significantly improves brachial flow-mediated vasodilation and reduces BP (Porkert et al., 2008)

Interaction of radiation- and bleomycin-induced lesions and influence of glutathione level on the interaction

Obara-Michlewska, M., Ruszkiewicz, J., Zielinska, M., Verkhratsky, A